Cairo, Egypt: Case Study: AVR with Antiphospholipid Syndrome


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Editor’s Note:

I saw this post of Ramy’s FB page (or maybe one of the perfusion groups on FB) and reached out to Ramy to submit this as a case study.  He has graciously forwarded the case study and I thank you Ramy.

Feel free to leave comments in the comments section-

Happy Saturday 🙂


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I performed today Aortic valve replacement with systemic lupus patient having antiphospholipid syndrome.

Materials :

1- Trumo heart lung machine
2- oxygenator Trumo sx 25
3- infusion pump having syringe with 4gm/ hr cyclocapron

Management  :

Systemic lupus erythematosus (SLE) is a multi-systemic autoimmune disorder characterized by a broad range of manifestations alongwith presence of antibodies in the blood directed against one or more components of cell nuclei.

Patients with SLE produce abnormal antibodies in their blood that target tissues within their own body rather than foreign infectious agents.

So, the only management is to keep ACT with a higher level to prevent clotting
Other consideration from anesthetic Dr. by using Cefuroxime 1500 mg and linezolid 600 mg were administered intravenous.(IV) as antibiotic prophylaxis. Anesthesia was induced with midazolam 2 mg, fentanyl 3 mcg/kg and thiopentone 150 mg IV.

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Meet the Author:


Ramy Mohamed


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