Platelet Gel Systems & Comparisons

“Although modest in terms of complexity, and clinical challenge, platelet gel does rear it’s head for those of us that are in accounts that employ the use of this modality.”

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Editor’s Note:

Today’s menu is less esoteric- and however bland, represents one of the many adjunct therapies and applications that perfusionists are involved in, that are within our scope of practice.

Although modest in terms of complexity, and clinical challenge, platelet gel does rear it’s head for those of us that are in accounts that employ the use of this modality.

Typically it manifests as an additional trip to some distant OR room, or maybe even another satellite hospital (non-heart), where we have a service contract, and of course, this requires assigned manpower, and may stretch our personnel staffing to its limits.   But it is what it is, and certainly a part of our daily practice.

Below is a simple comparison of some of the systems out there.

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Note: The results above have been obtained from references cited below and in some cases directly from the manufacturer’s product literature.  Perfusion.com, Inc. does not warranty the accuracy or validity of the above data, as pricing is subject to change and individual test results may vary significantly.  Clinical decisions to use a product should be based on in-depth research, careful analysis and physician direction.* Data obtained from manufacturer’s promotional literature.
References:

  1. Kevy, et al, Comparison of Methods for Point of Care Preparation of Autologous Platelet Gel, JECT, 2004; 36:28-35.
  2. Kevy, et al, Center for Blood Research; Presented at AMSECT – Hemostatis in Blood Management Meeting; April 2004
  3. Stammers, A.H., Trowbridge, C.C., et al, Establishment of a Quality Control Program for Platelet Gel Preparation: A Comparison of Four Commercial Devices – Society of Cardiovascular Anesthesiology Meeting: 9th Annual Update on Cardiopulmonary Bypass, March 2004
  4. Cobe Cardiovascular, Angel Whole Blood Separation, 2004 306700000 Rev A 10/04 5x increase in 10% of whole blood volume processed 5x in (0.10 x 60 ml) = 5x in 6 ml PRP
  5. Cobe Cardiovascular, Angel Whole Blood Separation, 2004 306700000 Rev A 10/04 15 min to process 40 ml/28 minutes to process 180 ml Time to process 120 ml = 15 min + {(28 min -15 min)/(180 ml – 40 ml)} x 80 ml = 22.4 min
  6. Process times of 15.5 min per pass presented Sept 24, 2005, California State Perfusion Society Meeting, Lake Tahoe, NV.
  7. Christensen, et, al,  Autologous platelet gel : An in vitro analysis of platelet-rich plasma using multiple cycles, JECT 2006,:38:249-253
  8. Fried D, Leo J, Weber F, Husain M, Cullen J.  Quantitative and Qualitative Analysis of Platelet-Rich PlasmaCollection Using the Haemonetics Cell Saver 5 in OpenHeart Surgery. JECT 2006;38:235-240
  9. Waters JH, Roberts KC. Database Review of Possible Factors Influencing Point-of-Care Platelet Gel Manufacture. JECT 2004;36:250-254

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