HEPARIN ONSET: Maximal at 1 minute past atrial delivery: Measured at radial artery. Note: 10-20% reduction in svr without affecting c.o. and or h.r. LUNG VS MUCOSAL: Mucosal requires larger doses- but can be reversed with 25-30% less protamine: greater postoperative blood loss associated with mucosal heparin- speculated to result from lower molecular weight & […]
HEPARIN ONSET: Maximal at 1 minute past atrial delivery: Measured at radial artery. Note: 10-20% reduction in svr without affecting c.o. and or h.r. LUNG VS MUCOSAL: Mucosal requires larger doses- but can be reversed with 25-30% less protamine: greater postoperative blood loss associated with mucosal heparin- speculated to result from lower molecular weight & […]