Why is my Patient Bleeding? A Snapshot of Hemostasis, Part II

Click on image to view source article Editor’s Note: We have all revisted this pathway intensively throughout our careers, and of course, we have all been clinically challenged by open-heart cases that test our fundamental understanding of coagulation theory in real time, at a level that certainly reflects a fairly deep dive into esoteric hematology. So i am keeping it simple, and found […]

Why is my Patient Bleeding? A Snapshot of Hemostasis

To view source article and take the Quiz- click on image above 🙂 Editor’s Note: Having just finished a case where we used Angiomax as our heparin substitute, I felt that the anticoagulation pathway, is truly a complex animal, and deserves a closer review. We have all revisted this pathway intensively throughout our careers, and of course, […]

Activated Clotting Time (ACT)

Activated Clotting Time (ACT) The ACT is a standardized measurement of the patients procoagulation or anticoagulation level.  The unit of measurement is the time (in seconds) that is required for an ACT counter to detect the formation of blood clot in a 2-3 milliliter sample of whole blood.  Normal ACT levels range from 100-130 seconds, […]

Coagulopathies & Treatment

Coagulopathies & Treatment The most common cause of intraoperative coagulopathy is thrombocytopenia (decrease in platelet count) secondary to hemodilution.  Blood loss that is replaced by crystalloid volume will progressively dilute platelet numbers as well as platelet entrapment on the surfaces of the extracorporeal circuit.  Associated with bypass is platelet migration to the spleen and reticuloendothelial […]