Blood Components

Separating Components from Whole Blood Fibrinogen Fibrinogen is a high molecular weight protein occurring in the plasma in quantities of 100 to 700 mg/dl.  In the presence of calcium ions it becomes the precursor for fibrin threads the foundation of the blood clot.  In terms of replacement therapy, a target value of 150 mg/dl may […]

Cryoprecipitate v1.0

Cryoprecipitate Cryoprecipitate contains 2 or more times the concentration of fibrinogen contained in plasma as well as increased levels of factor V and factor VIII.   Each unit however, contains only 50 ml, thus conceivably requiring several units of cryoprecipitate to be administered in order to achieve target ranges (>150 mg/dl) for depleted fibrinogen levels.  This […]